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腎臓内科のためのDDS技術
http://hdl.handle.net/10069/31248
http://hdl.handle.net/10069/312488d2017d1-ffb8-4afd-83cd-f15763804299
名前 / ファイル | ライセンス | アクション |
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DDS27_257.pdf (1.7 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2013-04-08 | |||||
タイトル | ||||||
タイトル | 腎臓内科のためのDDS技術 | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | fibrosis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | cationized gelatin | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | small interfering RNA | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | gene-cell hybrid therapy | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
小畑, 陽子
× 小畑, 陽子× 西野, 友哉× 河野, 茂 |
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著者別名 | ||||||
姓名 | Obata, Yoko | |||||
著者別名 | ||||||
姓名 | Nishino, Tomoya | |||||
著者別名 | ||||||
姓名 | Kohno, Shigeru | |||||
その他のタイトル | ||||||
その他のタイトル | Technologies of Drug Delivery System for Nephrology | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | 近年、慢性腎臓病が末期腎不全ならびに心血管疾患の危険因子であることが明らかとなってきており,慢性腎臓病への対策を講じることは透析導入患者数の増加に歯止めをかけると共に心血管疾患の発症を防止することにも繋がり、大変重要と考えられる。しかしながら、末期腎不全でみられる糸球体硬化や腎間質線維化に対する根本的な治療方法はいまだ確立されていない。そこで、本稿では、臓器線維化に対するdrug delivery system (DDS)を応用した再生誘導治療の試みを中心とした、腎臓内科分野におけるDDS技術について概説する。 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Chronic kidney disease (CKD) is known to be a risk factor for end stage renal disease (ESRD) and cardiovascular disease. Therefore, the development of new treatments for CKD is important and necessary. However, there is no established therapy for glomerulosclerosis and renal interstitial fibrosis, which are seen in the kidney of ESRD patients. Recent advances in basic research on the mechanism of fibrosis leads to discovery of fibrosis relating genes or factors. Some anti-fibrotic approaches for targeting these factors have been reported. In this review, we introduce several technologies and methodology using drug delivery system for fibrosis in nephrology. | |||||
書誌情報 |
Drug Delivery System 巻 27, 号 4, p. 257-266, 発行日 2012-12-28 |
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出版者 | ||||||
出版者 | 日本DDS学会 | |||||
出版者別言語 | ||||||
Japan Society of Drug Delivery System | ||||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 09135006 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 18812732 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.2745/dds.27.257 | |||||
権利 | ||||||
権利情報 | © 2012 日本DDS学会 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Drug Delivery System, 27(4), pp.257-266; 2012 |