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Predictors of Locoregional Recurrence in T1-2N0 Tongue Cancer Patients
http://hdl.handle.net/10069/33979
http://hdl.handle.net/10069/33979f1575839-54f7-448c-9f2e-1653fab97d87
名前 / ファイル | ライセンス | アクション |
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POR19_795.pdf (873.3 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2014-11-01 | |||||
タイトル | ||||||
タイトル | Predictors of Locoregional Recurrence in T1-2N0 Tongue Cancer Patients | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Neoadjuvant chemotherapy | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Recurrence | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Surgical margin | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Tongue cancer | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Yanamoto, Souichi
× Yanamoto, Souichi× Yamada, Shin-ichi× Takahashi, Hidenori× Kawasaki, Goro× Ikeda, Hisazumi× Shiraishi, Takeshi× Fujita, Shuichi× Ikeda, Tohru× Asahina, Izumi× Umeda, Masahiro |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Locoregional recurrence of oral tongue squamous cell carcinoma (OTSCC) has been considered a poor prognostic entity in terms of survival rate. The purpose of this study was to evaluate the incidence of locoregional recurrence and to identify significant risk factors for locoregional recurrence in early-stage OTSCC. We retrospectively reviewed the records of 58 patients who underwent radical surgery for T1-2N0 OTSCC. The local recurrence and regional recurrence rates were 10.3 % (6/58 patients) and 15.5 % (9/58 patients) in this study, respectively. The survival rate of patients with local recurrence was 66.7 %, which was significantly lower than that (96.2 %) of patients without local recurrence, whereas the survival rates of patients with or without regional recurrence were not significantly difference. Pattern of invasion (POI), neoadjuvant chemotherapy (NAC) and the status of the surgical margin were identified as factors influencing local recurrence. In particular, the status of the deep surgical margin was a high potential independent risk factor. The deep surgical margin was resected closely in many NAC-treated cases, suggesting that NAC may lead to local recurrence and a poor outcome. No efficacy of NAC was observed, suggesting that the standard treatment for early OTSCC is surgery alone. | |||||
書誌情報 |
Pathology & Oncology Research 巻 19, 号 4, p. 795-803, 発行日 2013-10 |
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出版者 | ||||||
出版者 | Springer Netherlands | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 12194956 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 15322807 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1007/s12253-013-9646-9 | |||||
権利 | ||||||
権利情報 | © 2013 Arányi Lajos Foundation. | |||||
権利 | ||||||
権利情報 | The final publication is available at link.springer.com | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Pathology & Oncology Research, 19(4), pp.795-803; 2013 |