WEKO3
アイテム
{"_buckets": {"deposit": "7badfe58-25a9-48ff-8b76-0115bad61e21"}, "_deposit": {"created_by": 2, "id": "716", "owners": [2], "pid": {"revision_id": 0, "type": "depid", "value": "716"}, "status": "published"}, "_oai": {"id": "oai:nagasaki-u.repo.nii.ac.jp:00000716", "sets": ["11"]}, "author_link": ["3498", "3500", "3495", "3490", "3497", "3502", "3496", "3504", "3510", "3492", "3509", "3488", "3493", "3489", "3508", "3506", "3499", "3501", "3494", "3507", "3503", "3505", "3491"], "item_2_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2020-04-15", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "1", "bibliographicPageStart": "281", "bibliographicVolumeNumber": "20", "bibliographic_titles": [{"bibliographic_title": "BMC Infectious Diseases"}]}]}, "item_2_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "BACKGROUND: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease that commonly has a lethal course caused by the tick-borne Huaiyangshan banyang virus [former SFTS virus (SFTSV)]. The viral load in various body fluids in SFTS patients and the best infection control measure for SFTS patients have not been fully established. CASE PRESENTATION: A 79-year-old man was bitten by a tick while working in the bamboo grove in Nagasaki Prefecture in the southwest part of Japan. Due to the occurrence of impaired consciousness, he was referred to Nagasaki University Hospital for treatment. The serum sample tested positive for SFTSV-RNA in the genome amplification assay, and he was diagnosed with SFTS. Furthermore, SFTSV-RNA was detected from the tick that had bitten the patient. He was treated with multimodal therapy, including platelet transfusion, antimicrobials, antifungals, steroids, and continuous hemodiafiltration. His respiration was assisted with mechanical ventilation. On day 5, taking the day on which he was hospitalized as day 0, serum SFTSV-RNA levels reached a peak and then decreased. However, the cerebrospinal fluid collected on day 13 was positive for SFTSV-RNA. In addition, although serum SFTSV-RNA levels decreased below the detectable level on day 16, he was diagnosed with pneumonia with computed tomography. SFTSV-RNA was detected in the bronchoalveolar lavage fluid on day 21. By day 31, he recovered consciousness completely. The pneumonia improved by day 51, but SFTSV-RNA in the sputum remained positive for approximately 4 months after disease onset. Strict countermeasures against droplet/contact infection were continuously conducted. CONCLUSIONS: Even when SFTSV genome levels become undetectable in the serum of SFTS patients in the convalescent phase, the virus genome remains in body fluids and tissues. It may be possible that body fluids such as respiratory excretions become a source of infection to others; thus, careful infection control management is needed.", "subitem_description_type": "Abstract"}]}, "item_2_description_63": {"attribute_name": "引用", "attribute_value_mlt": [{"subitem_description": "BMC infectious diseases, 20(1), art.no.281; 2020", "subitem_description_type": "Other"}]}, "item_2_publisher_33": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "BioMed Central Ltd."}]}, "item_2_relation_12": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "10.1186/s12879-020-05012-8", "subitem_relation_type_select": "DOI"}}]}, "item_2_rights_13": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "c The Author(s). 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you giveappropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article\u0027s Creative Commonslicence, unless indicated otherwise in a credit line to the material. If material is not included in the article\u0027s Creative Commonslicence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtainpermission directly from the copyright holder. To view a copy of this licence,visit http://creativecommons.org/licenses/by/4.0/.The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data."}]}, "item_2_source_id_8": {"attribute_name": "EISSN", "attribute_value_mlt": [{"subitem_source_identifier": "14712334", "subitem_source_identifier_type": "ISSN"}]}, "item_2_version_type_16": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Akagi, Kazumasa"}], "nameIdentifiers": [{"nameIdentifier": "3488", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Miyazaki, Taiga"}], "nameIdentifiers": [{"nameIdentifier": "3489", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Oshima, Kazuhiro"}], "nameIdentifiers": [{"nameIdentifier": "3490", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Umemura, Asuka"}], "nameIdentifiers": [{"nameIdentifier": "3491", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Shimada, Satoshi"}], "nameIdentifiers": [{"nameIdentifier": "3492", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Morita, Kouichi"}], "nameIdentifiers": [{"nameIdentifier": "3493", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Senju, Hiroaki"}], "nameIdentifiers": [{"nameIdentifier": "3494", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tashiro, Masato"}], "nameIdentifiers": [{"nameIdentifier": "3495", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Takazono, Takahiro"}], "nameIdentifiers": [{"nameIdentifier": "3496", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Saijo, Tomomi"}], "nameIdentifiers": [{"nameIdentifier": "3497", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kurihara, Shintaro"}], "nameIdentifiers": [{"nameIdentifier": "3498", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sekino, Motohiro"}], "nameIdentifiers": [{"nameIdentifier": "3499", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yamamoto, Kazuko"}], "nameIdentifiers": [{"nameIdentifier": "3500", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Imamura, Yoshifumi"}], "nameIdentifiers": [{"nameIdentifier": "3501", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Izumikawa, Koichi"}], "nameIdentifiers": [{"nameIdentifier": "3502", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yanagihara, Katsunori"}], "nameIdentifiers": [{"nameIdentifier": "3503", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Uda, Akihiko"}], "nameIdentifiers": [{"nameIdentifier": "3504", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Morikawa, Shigeru"}], "nameIdentifiers": [{"nameIdentifier": "3505", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yoshikawa, Tomoki"}], "nameIdentifiers": [{"nameIdentifier": "3506", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kurosu, Takeshi"}], "nameIdentifiers": [{"nameIdentifier": "3507", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Shimojima, Masayuki"}], "nameIdentifiers": [{"nameIdentifier": "3508", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Saijo, Masayuki"}], "nameIdentifiers": [{"nameIdentifier": "3509", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Mukae, Hiroshi"}], "nameIdentifiers": [{"nameIdentifier": "3510", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2020-12-18"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "BMCID20_281.pdf", "filesize": [{"value": "685.5 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 685500.0, "url": {"label": "BMCID20_281.pdf", "url": "https://nagasaki-u.repo.nii.ac.jp/record/716/files/BMCID20_281.pdf"}, "version_id": "78571ab5-c17a-431d-81c4-02b588618488"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "SFTS", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Viremia", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Encephalopathy", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Pneumonia", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Case report", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Detection of viral RNA in diverse body fluids in an SFTS patient with encephalopathy, gastrointestinal bleeding and pneumonia: a case report and literature review", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Detection of viral RNA in diverse body fluids in an SFTS patient with encephalopathy, gastrointestinal bleeding and pneumonia: a case report and literature review"}]}, "item_type_id": "2", "owner": "2", "path": ["11"], "permalink_uri": "http://hdl.handle.net/10069/39895", "pubdate": {"attribute_name": "公開日", "attribute_value": "2020-05-01"}, "publish_date": "2020-05-01", "publish_status": "0", "recid": "716", "relation": {}, "relation_version_is_last": true, "title": ["Detection of viral RNA in diverse body fluids in an SFTS patient with encephalopathy, gastrointestinal bleeding and pneumonia: a case report and literature review"], "weko_shared_id": -1}
Detection of viral RNA in diverse body fluids in an SFTS patient with encephalopathy, gastrointestinal bleeding and pneumonia: a case report and literature review
http://hdl.handle.net/10069/39895
http://hdl.handle.net/10069/39895a885e375-99cc-4ee2-861c-fd0ad542157a
名前 / ファイル | ライセンス | アクション |
---|---|---|
BMCID20_281.pdf (685.5 kB)
|
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2020-05-01 | |||||
タイトル | ||||||
タイトル | Detection of viral RNA in diverse body fluids in an SFTS patient with encephalopathy, gastrointestinal bleeding and pneumonia: a case report and literature review | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | SFTS | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Viremia | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Encephalopathy | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Pneumonia | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Case report | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Akagi, Kazumasa
× Akagi, Kazumasa× Miyazaki, Taiga× Oshima, Kazuhiro× Umemura, Asuka× Shimada, Satoshi× Morita, Kouichi× Senju, Hiroaki× Tashiro, Masato× Takazono, Takahiro× Saijo, Tomomi× Kurihara, Shintaro× Sekino, Motohiro× Yamamoto, Kazuko× Imamura, Yoshifumi× Izumikawa, Koichi× Yanagihara, Katsunori× Uda, Akihiko× Morikawa, Shigeru× Yoshikawa, Tomoki× Kurosu, Takeshi× Shimojima, Masayuki× Saijo, Masayuki× Mukae, Hiroshi |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | BACKGROUND: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease that commonly has a lethal course caused by the tick-borne Huaiyangshan banyang virus [former SFTS virus (SFTSV)]. The viral load in various body fluids in SFTS patients and the best infection control measure for SFTS patients have not been fully established. CASE PRESENTATION: A 79-year-old man was bitten by a tick while working in the bamboo grove in Nagasaki Prefecture in the southwest part of Japan. Due to the occurrence of impaired consciousness, he was referred to Nagasaki University Hospital for treatment. The serum sample tested positive for SFTSV-RNA in the genome amplification assay, and he was diagnosed with SFTS. Furthermore, SFTSV-RNA was detected from the tick that had bitten the patient. He was treated with multimodal therapy, including platelet transfusion, antimicrobials, antifungals, steroids, and continuous hemodiafiltration. His respiration was assisted with mechanical ventilation. On day 5, taking the day on which he was hospitalized as day 0, serum SFTSV-RNA levels reached a peak and then decreased. However, the cerebrospinal fluid collected on day 13 was positive for SFTSV-RNA. In addition, although serum SFTSV-RNA levels decreased below the detectable level on day 16, he was diagnosed with pneumonia with computed tomography. SFTSV-RNA was detected in the bronchoalveolar lavage fluid on day 21. By day 31, he recovered consciousness completely. The pneumonia improved by day 51, but SFTSV-RNA in the sputum remained positive for approximately 4 months after disease onset. Strict countermeasures against droplet/contact infection were continuously conducted. CONCLUSIONS: Even when SFTSV genome levels become undetectable in the serum of SFTS patients in the convalescent phase, the virus genome remains in body fluids and tissues. It may be possible that body fluids such as respiratory excretions become a source of infection to others; thus, careful infection control management is needed. | |||||
書誌情報 |
BMC Infectious Diseases 巻 20, 号 1, p. 281, 発行日 2020-04-15 |
|||||
出版者 | ||||||
出版者 | BioMed Central Ltd. | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 14712334 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1186/s12879-020-05012-8 | |||||
権利 | ||||||
権利情報 | c The Author(s). 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you giveappropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commonslicence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commonslicence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtainpermission directly from the copyright holder. To view a copy of this licence,visit http://creativecommons.org/licenses/by/4.0/.The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | BMC infectious diseases, 20(1), art.no.281; 2020 |