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    • Author/Creator:Holland, John J.
    • Title:Genetic Diversity of RNA Viruses [electronic resource] / edited by John J. Holland.
    • ISBN:9783642770111
    • Published/Created:Berlin, Heidelberg : Springer Berlin Heidelberg, 1992.
    • Physical Description:1 online resource.
    • Links:https://yale.idm.oclc.org/login?URL=http://dx.doi.org/10.1007/978-3-642-77011-1
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    • Local Notes:Access is available to the Yale community.
    • Access and use:Access restricted by licensing agreement.
    • Summary:The high mutation frequencies, population heterogeneity and rapid evolution potential of RNA viruses make them a prime object for investigation by virologists, immunologists and molecular biologists. This high level of interest is evident in this volume, which contains 14 concise and timely reviews of various areas of RNA virology. Standard RNA viruses (riboviruses) and retroviruses are reviewed, and facts and principles of their diversity and evolution are discussed. RNA virus mutation, population structure and rapid evolution (or paradoxical stasis) are examined in detail for a number of different RNA viruses. The problems created by the unusual genetics of RNA viruses are discussed: AIDS pathogenesis, antigenic change and vaccine problems, resistance to antiviraldrugs and origins of influenza outbreaks.
    • Variant and related titles:Springer ebooks.
    • Other formats:Printed edition:
    • Format:Book
    • Series:Current Topics in Microbiology and Immunology, 176
      Current Topics in Microbiology and Immunology, 176
    • Subjects:Medicine.
      Immunology.
      Microbiology.
      Medical virology.
      Allergy.
      Cytology.
    • Also listed under:SpringerLink (Online service)