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    • Title:Histophilus somni [electronic resource] : Biology, Molecular Basis of Pathogenesis, and Host Immunity / edited by Thomas J. Inzana.
    • ISBN:9783319295565
    • Publication:Cham : Springer International Publishing : Imprint: Springer, 2016.
    • Physical Description:VII, 160 p. : online resource.
    • Links:Online book
    • Yale Holdings

       
    • Local Notes:Access is available to the Yale community.
    • Access and use:Access restricted by licensing agreement.
    • Summary:This volume reviews the current understanding of the taxonomy, disease syndromes, genetics, biology, and pathogenic factors of Histophilus somni, as well as the host immune response to this pathogen. H. somni is one of the most important bacterial pathogens in cattle and other ruminants, and its virulence factors are highly conserved with Haemophilus influenzae and other members of the Pasteurellaceae. H. somni has been recognized as a major cause of thrombotic meningoencephalitis, respiratory disease syndromes, myocarditis, reproductive disease syndromes, polyarthritis, mastitis, ocular disease, and septicemia. The only known habitats of H. somni are the mucosal surfaces of ruminants, making this bacterium an opportunistic pathogen. Although it is capable of causing inflammation at systemic sites and is toxic to epithelial and phagocytic cells, the bacterium’s wide array of virulence factors act primarily as a defense against, or to escape recognition from, host innate and adaptive immunity.
    • In_:Springer eBooks
    • Variant and related titles:Springer ebooks.
    • Other formats:Printed edition:
    • Format:Book
    • Series:Current Topics in Microbiology and Immunology, 396
      Current topics in microbiology and immunology ; 396.
    • Contents:Taxonomy of Histophilus somni -- Histophilosis as a Natural Disease -- Histophilus somni Genomics and Genetics -- Interactions on Histophilus somni with Host Cells -- Histophilus somni Surface Proteins -- Host Immune Response to Histophilus somni -- The Many Facets of Lipooligosaccharide as a Virulence Factor of Histophilus somni -- Exopolysaccharide Production and Biofilm Formation by Histophilus somni.
    • Subjects:Medicine.
      Medical microbiology.
      Veterinary medicine.
      Bacteriology.
    • Also listed under:Inzana, Thomas J.
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