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Abnormal pontine activation in pathological laughing as shown by functional magnetic resonance imaging
http://hdl.handle.net/10098/1827
http://hdl.handle.net/10098/18275955bc88-6a5b-4a53-9c90-84d4bf4a13eb
名前 / ファイル | ライセンス | アクション |
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Abnormal_pontine_activation_in_pathological_laughing.pdf (658.8 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2009-01-05 | |||||
タイトル | ||||||
タイトル | Abnormal pontine activation in pathological laughing as shown by functional magnetic resonance imaging | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_1843 | |||||
資源タイプ | other | |||||
著者 |
KOSAKA, H
× KOSAKA, H× OMATA, N× OMORI, M× SHIMOYAMA, T× MURATA, T× KASHIKURA, K× TAKAHASHI, T× MURAYAMA, J× YONEKURA, Y× WADA, Y |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | To explore the aetiology of pathological laughing, a 65-year-old woman with pathological laughing was examined by 3-T functional magnetic resonance imaging (fMRI) before and after treatment with drugs. Here, we report that the patient consistently showed exaggerated pontine activation during the performance of three tasks before treatment, whereas abnormal pontine activation was no longer found after successful treatment with the selective serotonin reuptake inhibitor, paroxetine. Our findings in this first fMRI study of pathological laughing suggest that serotonergic replacement decreases the aberrant activity in a circuit that involves the pons. | |||||
書誌情報 |
Journal of neurology, neurosurgery and psychiatry 巻 77, 号 12, p. 1376-1380, 発行日 2006-12 |
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出版者 | ||||||
出版者 | BMJ Publishing Group | |||||
書誌レコードID | ||||||
識別子タイプ | NCID | |||||
関連識別子 | TD00006313 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1136/jnnp.2005.073288 | |||||
著者版フラグ | ||||||
出版タイプ | AO | |||||
出版タイプResource | http://purl.org/coar/version/c_b1a7d7d4d402bcce |