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Fabrication and properties of alginate/calcium phosphate hybrid beads: A comparative study
http://hdl.handle.net/10228/00008014
http://hdl.handle.net/10228/00008014cf6e9e43-72fd-43e1-8ca0-87f3552975c4
名前 / ファイル | ライセンス | アクション |
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BME-206012.pdf (995.6 kB)
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Item type | 学術雑誌論文 = Journal Article(1) | |||||||||||
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公開日 | 2021-01-27 | |||||||||||
資源タイプ | ||||||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
資源タイプ | journal article | |||||||||||
タイトル | ||||||||||||
タイトル | Fabrication and properties of alginate/calcium phosphate hybrid beads: A comparative study | |||||||||||
言語 | ||||||||||||
言語 | eng | |||||||||||
著者 |
Tripathi, Garima
× Tripathi, Garima× 宮崎, 敏樹
WEKO
6369
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抄録 | ||||||||||||
内容記述タイプ | Abstract | |||||||||||
内容記述 | Microbeads for bone repair have been widely studied because they can be conveniently used in clinical applications. This study concerns the preparation, physical properties and in vitro characterisation of different types of alginate / calcium phosphate (CaP) ceramic microbeads, which were designed for use as drug delivery systems and bone-regeneration matrices. Hybrid microbeads were successfully prepared from sodium alginate and various CaP, namely α-tricalcium phosphate, β-tricalcium phosphate and hydroxyapatite using the liquid droplet method. Porosity, swelling properties and in vitro degradation of the microbeads in aqueous environment were significantly changed by the added CaP. The compressive strength of the blocks fabricated from the beads was around 120 MPa irrespective of the type of CaP. The initial release rate of the model drug methylene blue was suppressed by the addition of CaP. The alginate-CaP composite beads hold promising potential as an encapsulation carrier of drugs and component of bone substitutes. | |||||||||||
書誌情報 |
Bio-Medical Materials and Engineering 巻 32, 号 1, p. 15-27, 発行日 2021-01-21 |
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出版社 | ||||||||||||
出版者 | IOS Press | |||||||||||
DOI | ||||||||||||
関連タイプ | isVersionOf | |||||||||||
識別子タイプ | DOI | |||||||||||
関連識別子 | https://doi.org/10.3233/BME-206012 | |||||||||||
日本十進分類法 | ||||||||||||
主題Scheme | NDC | |||||||||||
主題 | 492 | |||||||||||
ISSN | ||||||||||||
収録物識別子タイプ | ISSN | |||||||||||
収録物識別子 | 0959-2989 | |||||||||||
ISSN | ||||||||||||
収録物識別子タイプ | ISSN | |||||||||||
収録物識別子 | 1878-3619 | |||||||||||
著作権関連情報 | ||||||||||||
権利情報 | Copyright (c) IOS Press. The final publication is available at IOS Press through http://dx.doi.org/10.3233/BME-206012 | |||||||||||
キーワード | ||||||||||||
主題Scheme | Other | |||||||||||
主題 | Alginate | |||||||||||
キーワード | ||||||||||||
主題Scheme | Other | |||||||||||
主題 | calcium phosphate | |||||||||||
キーワード | ||||||||||||
主題Scheme | Other | |||||||||||
主題 | microbeads | |||||||||||
キーワード | ||||||||||||
主題Scheme | Other | |||||||||||
主題 | in vitro drug release | |||||||||||
キーワード | ||||||||||||
主題Scheme | Other | |||||||||||
主題 | in vitro degradation | |||||||||||
出版タイプ | ||||||||||||
出版タイプ | AM | |||||||||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||||||
査読の有無 | ||||||||||||
値 | yes | |||||||||||
研究者情報 | ||||||||||||
https://hyokadb02.jimu.kyutech.ac.jp/html/323_ja.html | ||||||||||||
論文ID(連携) | ||||||||||||
10360674 | ||||||||||||
連携ID | ||||||||||||
8532 | ||||||||||||
著者別名 | ||||||||||||
姓名 | Tripathi, G. | |||||||||||
著者別名 | ||||||||||||
姓名 | Miyazaki, Toshiki | |||||||||||
言語 | en | |||||||||||
姓名 | 宮崎, 敏樹 | |||||||||||
言語 | ja | |||||||||||
姓名 | ミヤザキ, トシキ | |||||||||||
言語 | ja-Kana |