Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/115499
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Título: | Pogo-like transposases have been repeatedly domesticated into CENP-B-related proteins |
Autor: | Mateo, Lidia CSIC; González Pérez, Josefa CSIC ORCID | Palabras clave: | Pogo Drosophila Exaptation Functional domain Holocentric chromosomes |
Fecha de publicación: | 2014 | Editor: | Oxford University Press | Citación: | Genome Biology and Evolution 6(8): 2008-2016 (2014) | Resumen: | The centromere is a chromatin region that is required for accurate inheritance of eukaryotic chromosomes during cell divisions. Among the different centromere-associated proteins (CENP) identified, CENP-B has been independently domesticated from a pogo-like transposase twice: Once in mammals and once in fission yeast. Recently, a third independent domestication restricted to holocentric lepidoptera has been described. In this work, we take advantage of the high-quality genome sequence and the wealth of functional information available for Drosophila melanogaster to further investigate the possibility of additional independent domestications of pogo-like transposases into host CENP-B related proteins. Our results showed that CENP-B related genes are not restricted to holocentric insects. Furthermore, we showed that at least three independent domestications of pogo-like transposases have occurred in metazoans. Our results highlight the importance of transposable elements as raw material for the recurrent evolution of important cellular functions. © The Author(s) 2014. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. | Versión del editor: | http://dx.doi.org/10.1093/gbe/evu153 | URI: | http://hdl.handle.net/10261/115499 | DOI: | 10.1093/gbe/evu153 | Identificadores: | doi: 10.1093/gbe/evu153 issn: 1759-6653 |
Aparece en las colecciones: | (IBE) Artículos |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
pogo-like_transposases_Mateo.pdf | 1,01 MB | Adobe PDF | Visualizar/Abrir |
CORE Recommender
PubMed Central
Citations
21
checked on 13-feb-2024
SCOPUSTM
Citations
31
checked on 15-abr-2024
WEB OF SCIENCETM
Citations
30
checked on 23-feb-2024
Page view(s)
342
checked on 19-abr-2024
Download(s)
265
checked on 19-abr-2024