Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/212262COMPARTIR / EXPORTAR:
 SHARE
 CORE
BASE
|
|
| Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
| Título: | One-pot synthesis and SAR study of cis-2,6-dialkyl-4-chloro-tetrahydropyrans |
Autor: | Miranda, Pedro O. CSIC ORCID ; León, Leticia G.; Martín, Víctor S. CSIC ORCID; Padrón, Juan I. CSIC ORCID ; Padrón, José M. | Palabras clave: | Marine drugs Halogenated tetrahydropyrans Solid tumors Drug design Structure–activity relationship |
Fecha de publicación: | 15-jun-2006 | Editor: | Elsevier | Citación: | Bioorganic and Medicinal Chemistry Letters 16(12): 3135-3138 (2006) | Resumen: | A series of cis-2,6-dialkyl-4-chloro-tetrahydropyrans were prepared by means of an iron(III)-catalyzed process. The in vitro antiproliferative activities were examined in the human solid tumor cell lines A2780, SW1573, and WiDr. The results show that the presence of bulky substituents favors the Prins cyclization leading to new products with better activity profile against all cell lines tested. | Versión del editor: | https://doi.org/10.1016/j.bmcl.2006.03.064 | URI: | http://hdl.handle.net/10261/212262 | DOI: | 10.1016/j.bmcl.2006.03.064 | ISSN: | 0960-894X | E-ISSN: | 1464-3405 |
| Aparece en las colecciones: | (IPNA) Artículos |
Ficheros en este ítem:
| Fichero | Descripción | Tamaño | Formato | |
|---|---|---|---|---|
| accesoRestringido.pdf | Artículo principal | 16,34 kB | Adobe PDF |  Visualizar/Abrir |
CORE Recommender
SCOPUSTM
Citations
14
checked on 17-abr-2024
WEB OF SCIENCETM
Citations
15
checked on 29-feb-2024
Page view(s)
125
checked on 23-abr-2024
Download(s)
26
checked on 23-abr-2024
Google ScholarTM
Check
Altmetric
Altmetric
Este item está licenciado bajo una Licencia Creative Commons
