Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/41236
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Título: | An antennal-specific role for bowl in repressing supernumerary appendage development in Drosophila |
Autor: | Bras-Pereira, Catarina CSIC ORCID; Casares, Fernando CSIC ORCID | Palabras clave: | Bowl Antennal development Proximo-distal axis Wingless Decapentaplegic Drosophila Evolution |
Fecha de publicación: | 10-jul-2008 | Editor: | Elsevier | Citación: | Mechanisms of Development 125(9-10): 809-821 (2008) | Resumen: | In Drosophila, antennae and legs are serially homologous appendages, and yet they develop into organs of very different structure and function. This implies that different genetic mechanisms operate onto a common developmental ground state to produce antennae and legs. Still few such mechanisms have been uncovered. During leg development, bowl, a member of the odd-skipped gene family, has been shown to participate in the formation of the leg segmental joints. Here we report that, in the antennal disc, bowl has a dramatically different role: bowl is expressed in the ventral antennal disc to prevent inappropriate expression of wg early during development. The removal of bowl function leads to the activation of wg in the dpp-expressing domain. This ectopic expression of wg, together with dpp, results in a new proximo–distal axis that promotes non-autonomous antennal duplications. The role of bowl in suppressing a supernumerary PD axis is maintained even when the antennal disc is homeotically transformed into a leg-like appendage. Therefore, bowl is part of a genetic program that suppresses the formation of supernumerary appendages specifically in the fly’s head. | Descripción: | 13 páginas, 7 figuras. | Versión del editor: | http://dx.doi.org/10.1016/j.mod.2008.07.002 | URI: | http://hdl.handle.net/10261/41236 | DOI: | 10.1016/j.mod.2008.07.002 | ISSN: | 0925-4773 | E-ISSN: | 1872-6356 |
Aparece en las colecciones: | (CABD) Artículos |
Mostrar el registro completo
CORE Recommender
SCOPUSTM
Citations
6
checked on 17-abr-2024
WEB OF SCIENCETM
Citations
6
checked on 22-feb-2024
Page view(s)
391
checked on 19-abr-2024
Google ScholarTM
Check
Altmetric
Altmetric
NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.