Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/54336
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Título: | Dietary arginine and repeated handling increase disease resistance and modulate innate immune mechanisms of Senegalese sole (Solea senegalensis Kaup, 1858) |
Autor: | Costas, Benjamín; Conceição, Luis E. C.; Dias, Jorge; Novoa, Beatriz CSIC ORCID; Figueras Huerta, Antonio CSIC ORCID ; Afonso, António | Palabras clave: | Bacterial challenges Immune-related genes Nitric oxide Respiratory burst activity Stress response |
Fecha de publicación: | 2011 | Editor: | Elsevier | Citación: | Fish and Shellfish Immunology 31(6): 838-847 (2011) | Resumen: | Stress is known to impair immune function and disease resistance in fish. In the present study, repeated handling was employed as a chronic stressor in order to verify whether its attributed immunosuppressive effects could be minimized by dietary arginine supplementation. Therefore, Senegalese sole (Solea senegalensis) were air exposed daily for 3 min during 14 days (handling) or left undisturbed (control). In addition, both control and handled specimens were fed 3 diets with graded levels of arginine (Arg 4.4, Arg 5.7 and Arg 6.9 g 16 g 1 N). Following the 14 days stress challenge and feeding on those diets, fish were infected with Photobacterium damselae subsp. piscicida (strain PC566.1; LD50 5 103 cfu mL 1) and fed the same experimental diets. Respiratory burst activity and nitric oxide production of headekidney leucocytes increased parallel to dietary arginine supplementation. HIF-1, HAMP-1, MIP1-alpha and gLYS expression values and some humoral parameters augmented in control specimens fed the Arg 5.7 and Arg 6.9 diets. Interestingly, repeated acute stress increased both disease resistance and some innate immune mechanisms in handled fish. The role of dietary arginine and repeated handling on Senegalese sole innate immunity and disease resistance are discussed. | Descripción: | 10 páginas, 4 figuras, 4 tablas | Versión del editor: | http://dx.doi.org/10.1016/j.fsi.2011.07.024 | URI: | http://hdl.handle.net/10261/54336 | DOI: | 10.1016/j.fsi.2011.07.024 | ISSN: | 1050-4648 |
Aparece en las colecciones: | (IIM) Artículos |
Mostrar el registro completo
CORE Recommender
SCOPUSTM
Citations
99
checked on 24-abr-2024
WEB OF SCIENCETM
Citations
87
checked on 25-feb-2024
Page view(s)
319
checked on 24-abr-2024
Google ScholarTM
Check
Altmetric
Altmetric
NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.