{"_buckets": {"deposit": "bdca4ee1-649c-4835-ae76-34e9eab77129"}, "_deposit": {"created_by": 4, "id": "2352", "owners": [4], "pid": {"revision_id": 0, "type": "depid", "value": "2352"}, "status": "published"}, "_oai": {"id": "oai:hama-med.repo.nii.ac.jp:00002352", "sets": ["11"]}, "author_link": [], "item_3_biblio_info_5": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2009-11-09", "bibliographicIssueDateType": "Issued"}, "bibliographicPageEnd": "534", "bibliographicPageStart": "529", "bibliographicVolumeNumber": "13", "bibliographic_titles": [{"bibliographic_title": "Int J Neuropsychopharmacol"}]}]}, "item_3_description_30": {"attribute_name": "フォーマット", "attribute_value_mlt": [{"subitem_description": "application/pdf", "subitem_description_type": "Other"}]}, "item_3_description_9": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "The aim of the present study was to investigate metabolite alterations in the hippocampal formation as they relate to aggression in high-functioning adults with autism. We measured concentrations of N-acetylaspartate (NAA), choline-containing compounds (Cho), and creatine plus phosphocreatine (Cr+PCr) in the hippocampal formation by proton magnetic resonance spectroscopy in 12 non-medicated male subjects with autism and 12 age- and sex-matched controls. Aggression was scored in the autistic subjects using the Buss-Perry Aggression Questionnaire. The concentrations of Cho and Cr+PCr in the hippocampal formation in autistic subjects were significantly higher than the corresponding values in control subjects, and a significant positive correlation was observed between the concentrations of these metabolites in the hippocampal formation and scores on the Buss-Perry Aggression Questionnaire in autistic subjects. Results suggest that high-functioning adult subjects with autism have abnormal metabolite concentrations in the hippocampal formation, which may in part account for their aggression.", "subitem_description_type": "Abstract"}]}, "item_3_publisher_6": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "CINP"}]}, "item_3_relation_28": {"attribute_name": "出版社DOI", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "10.1017/S1461145709990952", "subitem_relation_type_select": "DOI"}}]}, "item_3_rights_7": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "Copyright CINP"}]}, "item_3_select_2": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"subitem_select_item": "Journal Article", "subitem_select_language": "en"}]}, "item_3_source_id_19": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "14611457", "subitem_source_identifier_type": "ISSN"}]}, "item_3_version_type_32": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Suzuki, Katsuaki"}]}, {"creatorNames": [{"creatorName": "Nishimura, Katsuhiko"}]}, {"creatorNames": [{"creatorName": "Sugihara, Genichi"}]}, {"creatorNames": [{"creatorName": "Nakamura, Kazuhiko"}]}, {"creatorNames": [{"creatorName": "Tsuchiya, Kenji J."}]}, {"creatorNames": [{"creatorName": "Matsumoto, Kaori"}]}, {"creatorNames": [{"creatorName": "Takebayashi, Kiyokazu"}]}, {"creatorNames": [{"creatorName": "Isoda, Haruo"}]}, {"creatorNames": [{"creatorName": "Sakahara, Harumi"}]}, {"creatorNames": [{"creatorName": "Sugiyama, Toshiro"}]}, {"creatorNames": [{"creatorName": "Tsujii, Masatsugu"}]}, {"creatorNames": [{"creatorName": "Takei, Nori"}]}, {"creatorNames": [{"creatorName": "Mori, Norio"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-08-27"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "IntJNP9-1.pdf", "filesize": [{"value": "115.1 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 115100.0, "url": {"label": "IntJNP9-1.pdf", "url": "https://hama-med.repo.nii.ac.jp/record/2352/files/IntJNP9-1.pdf"}, "version_id": "67061e56-1247-4a78-a74f-49052fa7a1d4"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Aggression", "subitem_subject_scheme": "Other"}, {"subitem_subject": "autism", "subitem_subject_scheme": "Other"}, {"subitem_subject": "hippocampus", "subitem_subject_scheme": "Other"}, {"subitem_subject": "magnetic resonance spectroscopy", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Metabolite alterations in the hippocampus of high-functioning adult subjects with autism", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Metabolite alterations in the hippocampus of high-functioning adult subjects with autism", "subitem_title_language": "en"}]}, "item_type_id": "3", "owner": "4", "path": ["11"], "permalink_uri": "http://hdl.handle.net/10271/2409", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2013-08-27"}, "publish_date": "2013-08-27", "publish_status": "0", "recid": "2352", "relation": {}, "relation_version_is_last": true, "title": ["Metabolite alterations in the hippocampus of high-functioning adult subjects with autism"], "weko_shared_id": -1}
Metabolite alterations in the hippocampus of high-functioning adult subjects with autism
http://hdl.handle.net/10271/2409
http://hdl.handle.net/10271/2409