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Effect of target localization on the sensitivity of a localized surface plasmon resonance biosensor based on subwavelength metallic nanostructures
Cited 52 time in
Web of Science
Cited 53 time in Scopus
- Authors
- Issue Date
- 2009-04
- Publisher
- Optical Society of America
- Citation
- J. Opt. Soc. Am. A 26, 1027-1034 (2009)
- Abstract
- A localized surface plasmon resonance (LSPR) biosensor using surface relief nanostructures was investigated
to evaluate the importance of target localization on the sensitivity enhancement. The LSPR device was modeled
as periodic metallic nanowires with a square profile on a gold film and the target as a self-assembled
monolayer in buffer solution. The numerical results using rigorous coupled-wave analysis and the finitedifference
time domain method demonstrated localized plasmonic fields induced by the surface nanostructure
from which the effect of target localization on the sensitivity was quantitatively analyzed. Interestingly, it was
found that target localization on nanowire sidewalls improves sensitivity significantly because of strong overlap
with localized plasmonic fields. An LSPR structure optimized for a localized target on sidewalls provides
sensitivity enhancement per unit target volume by more than 20 times in water ambience.
- ISSN
- 1084-7529 (print)
1520-8532 (online)
- Language
- English
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