Adaptive living skills, sleep problems, and mental health problems in adults with 22q11.21 deletion syndrome
Date
2023-03-23Author
Leader, Geraldine
Curtin, Andrea
Shprintzen, Robert J.
Whelan, Sally
Coyne, Rory
Mannion, Arlene
Metadata
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Recommended Citation
Leader, Geraldine, Curtin, Andrea, Shprintzen, Robert J., Whelan, Sally, Coyne, Rory, & Mannion, Arlene. (2023). Adaptive living skills, sleep problems, and mental health disorders in adults with 22q11.21 deletion syndrome. Research in Developmental Disabilities, 136, 104491. doi: https://doi.org/10.1016/j.ridd.2023.104491
Published Version
Abstract
Background
22q11.21 deletion syndrome (22q11DS) is a neurodevelopmental syndrome caused by a microdeletion of genes at the 22q11.21 locus. It has a prevalence of 1:2000. This study investigated the prevalence of adaptive living skills, sleep problems, and mental health disorders in adults with 22q11DS and examined the relationship between these factors.
Methods
Parents with an adult son or daughter with 22q11DS completed the following: A bespoke Demographic Information Questionnaire, Sleep Questionnaire (SQ-SP), Psychopathology in Autism Checklist (PAC), and Activities of Daily Living (ADL) scale. Descriptive statistics, correlations, and one-way between groups analysis of variance (ANOVA) were conducted.
Results
Mental health difficulties, sleep problems, and low levels of adaptive living skills are prevalent in adults with 22q11DS. Strong positive correlations were identified between sleep problems, depression, and anxiety subscale scores and moderate negative correlations between depression, psychosis, and activities of daily living skills.
Conclusion
Adults with 22q11DS need screening and treatment for mental health and sleep problems.
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Except where otherwise noted, this item's license is described as Attribution 4.0 International (CC BY 4.0)
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