Isolation and characterization of piscine osteonectin and downregulation of Its expression by PTH-related protein

Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.1/3908

Título:	Isolation and characterization of piscine osteonectin and downregulation of Its expression by PTH-related protein
Autor:	Redruello, Begoña Estêvão, M. Dulce Rotllant, J. Guerreiro, P. M. Anjos, Liliana Canario, Adelino V. M. Power, Deborah
Palavras-chave:	Osteonectin Extracellular matrix Fish skeleton PTH-related peptide Scales
Data:	2005
Citação:	Begoña Redruello; Estêvão, Maria Dulce da Mota Antunes de Oliveira; Josep Rotlland; Pedro M. Guerreiro; Liliana I. Anjos; Adelino V. M. Canário; Deborah M. Power. Isolation and Characterization of Piscine Osteonectin and, JOURNAL OF BONE AND MINERAL RESEARCH, 20, 4, 682-692, 2005
Resumo:	The skeleton is the main source of osteonectin mRNA in adults of the seawater teleost sea bream Sparus auratus. It is expressed by cells forming the basement membrane of calcifying tissue indicating that, as in mammals, it may play a role in osteoblast differentiation. PTHrP induced downregulation of osteonectin mRNA in vitro in scales, a mineralizing tissue with bone-like metabolism. This indicates a means to redirect calcium to activities such as vitellogenesis when this ion is in high demand.
Peer review:	yes
URI:	http://hdl.handle.net/10400.1/3908
DOI:	http://dx.doi.org/10.1359/JBMR.041201
Aparece nas colecções:	ESS2-Artigos (em revistas ou actas indexadas) CCM2-Artigos (em revistas ou actas indexadas)

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