Utilize este identificador para referenciar este registo:
http://hdl.handle.net/10400.7/589
Título: | Ensembl regulation resources |
Autor: | Zerbino, Daniel R. Johnson, Nathan Juetteman, Thomas Sheppard, Dan Wilder, Steven P. Lavidas, Ilias Nuhn, Michael Perry, Emily Raffaillac-Desfosses, Quentin Sobral, Daniel Keefe, Damian Gräf, Stefan Ahmed, Ikhlak Kinsella, Rhoda Pritchard, Bethan Brent, Simon Amode, Ridwan Parker, Anne Trevanion, Steven Birney, Ewan Dunham, Ian Flicek, Paul |
Palavras-chave: | Genome DNA |
Data: | 24-Nov-2015 |
Editora: | Oxford University Press |
Citação: | Zerbino, D.R., Johnson, N., Juetteman, T. et al. Ensembl regulation resources. Database (2015) Vol. 2015: article ID bav119; doi:10.1093/database/bav119 |
Resumo: | New experimental techniques in epigenomics allow researchers to assay a diversity of highly dynamic features such as histone marks, DNA modifications or chromatin structure. The study of their fluctuations should provide insights into gene expression regulation, cell differentiation and disease. The Ensembl project collects and maintains the Ensembl regulation data resources on epigenetic marks, transcription factor binding and DNA methylation for human and mouse, as well as microarray probe mappings and annotations for a variety of chordate genomes. From this data, we produce a functional annotation of the regulatory elements along the human and mouse genomes with plans to expand to other species as data becomes available. Starting from well-studied cell lines, we will progressively expand our library of measurements to a greater variety of samples. Ensembl's regulation resources provide a central and easy-to-query repository for reference epigenomes. As with all Ensembl data, it is freely available at http://www.ensembl.org, from the Perl and REST APIs and from the public Ensembl MySQL database server at ensembldb.ensembl.org.Database URL: http://www.ensembl.org. |
Peer review: | yes |
URI: | http://hdl.handle.net/10400.7/589 |
DOI: | 10.1093/database/bav119 |
Versão do Editor: | http://database.oxfordjournals.org/content/2016/bav119.long |
Aparece nas colecções: | BCBU- Artigos |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
---|---|---|---|---|
Database-2016-Zerbino-database_bav119.pdf | artigo principal | 1,98 MB | Adobe PDF | Ver/Abrir |
Supplemental_Methods.docx | material suplementar 1 | 535,52 kB | Microsoft Word XML | Ver/Abrir |
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