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http://hdl.handle.net/10400.7/91
Título: | Nonequilibrium model for estimating parameters of deleterious mutations |
Autor: | Gordo, I. Dionisio, F. |
Palavras-chave: | Evolution Genetic Variation/genetics Genetics, Population/methods Models, Genetic Mutation/genetics Population Dynamics Selection, Genetic |
Data: | 18-Mar-2005 |
Editora: | American Physical Society |
Citação: | Gordo, I., Dionisio, F. (2005). Nonequilibrium model for estimating parameters of deleterious mutations. Phys. Rev. E. 71(3), 031907 |
Resumo: | Deleterious mutations are of extreme evolutionary importance because, even though they are eliminated by natural selection, their continuous pressure creates a pool of variability in natural populations. They are of potential relevance for the existence of several features in evolution, such as sexual reproduction, and pose a risk to small asexual populations. Despite their extreme importance, the deleterious mutation rate and the effects of each mutation on fitness are poorly known quantities. Here we analyze a simple model that can be applied to simple experiments, in microorganisms, aiming at the quantification of these values. |
URI: | http://hdl.handle.net/10400.7/91 |
DOI: | 10.1103/PhysRevE.71.031907 |
ISSN: | ISSN: 1539-3755 |
Aparece nas colecções: | EB - Articles |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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Gordo,I._Phys.Rev._ (2005).pdf | main article | 104,85 kB | Adobe PDF | Ver/Abrir |
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