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Pilot study to estimate the safety and effectiveness of hydroxyurea and methotrexate recurrent langerhans cell histiocytosis (LCH-HU-pilot)
http://hdl.handle.net/10422/00013503
http://hdl.handle.net/10422/0001350352c6c069-3d0e-4698-b02f-08df267b96a8
名前 / ファイル | ライセンス | アクション |
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MD.0000000000031475 (477.5 kB)
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This is an open access article distributed under the Creative Commons
Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2023-02-22 | |||||
タイトル | ||||||
タイトル | Pilot study to estimate the safety and effectiveness of hydroxyurea and methotrexate recurrent langerhans cell histiocytosis (LCH-HU-pilot) | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | hydroxyurea | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | langerhans cell histiocytosis | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | methotrexate | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | relapse | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
SAKAMOTO, Kenichi
× SAKAMOTO, Kenichi× KIKUCHI, Kayoko× SAKO, Mayumi× KATO, Miho× TAKIMOTO, Tetsuya× SHIODA, Yoko |
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著者別名 |
坂本, 謙一
× 坂本, 謙一 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | This study was a non-blinded, multicenter, single-arm study. Recurrent (relapsed) LCH is defined as the appearance of new lesions or the enlargement of preexisting lesions due to LCH. In this study, all patients received hydroxyurea, and if the treatment response was unsatisfactory, methotrexate was added. The duration of treatment was 48 weeks. The primary endpoint was the rate of non-active disease achievement, which was 24 weeks after initiating hydroxyurea administration. No active disease is defined as the resolution of all the signs and symptoms related to LCH. | |||||
書誌情報 |
en : Medicine (United States) 巻 101, 号 50, 発行日 2022-12-16 |
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出版者 | ||||||
出版者 | Lippincott Williams and Wilkins | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0025-7974 | |||||
PMID | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | PMID | |||||
関連識別子 | 36550910 | |||||
PMCID | ||||||
識別子タイプ | URI | |||||
関連識別子 | http://www.ncbi.nlm.nih.gov/pmc/articles/pmc9771280/ | |||||
関連名称 | PMC9771280 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1097/md.0000000000031475 | |||||
関連名称 | 10.1097/md.0000000000031475 | |||||
権利 | ||||||
権利情報 | © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
資源タイプ | ||||||
内容記述タイプ | Other | |||||
内容記述 | Journal Article |