Inulin is an extremely adaptable polysaccharides consisting of glucopyranose end-capped (β-1,2) fructose repeating units and, as it is, can be classified as an inherently multifunctional polymeric scaffold. It may be further functionalized employing mild conditions to give rise desired biological and physicochemical properties exploitable for targeted anticancer applications (e.g., active targeting toward specific cytotypes, self-assembling behavior, selective cytoxicity and hyperthermia features). In this review, the main chemical features and the inulin derivatives applications in the field of targeted anticancer therapy is reported and discussed

G. Giammona, N. Mauro, C. Scialabba (2016). Inulin for Cancer Therapy: Present and Perspectives. INTERNATIONAL JOURNAL OF PHARMA RESEARCH AND REVIEW, 5, 63-69.

Inulin for Cancer Therapy: Present and Perspectives

GIAMMONA, Gaetano;Mauro, Nicolò;SCIALABBA, Cinzia
2016-01-01

Abstract

Inulin is an extremely adaptable polysaccharides consisting of glucopyranose end-capped (β-1,2) fructose repeating units and, as it is, can be classified as an inherently multifunctional polymeric scaffold. It may be further functionalized employing mild conditions to give rise desired biological and physicochemical properties exploitable for targeted anticancer applications (e.g., active targeting toward specific cytotypes, self-assembling behavior, selective cytoxicity and hyperthermia features). In this review, the main chemical features and the inulin derivatives applications in the field of targeted anticancer therapy is reported and discussed
2016
Settore CHIM/09 - Farmaceutico Tecnologico Applicativo
G. Giammona, N. Mauro, C. Scialabba (2016). Inulin for Cancer Therapy: Present and Perspectives. INTERNATIONAL JOURNAL OF PHARMA RESEARCH AND REVIEW, 5, 63-69.
File in questo prodotto:
File Dimensione Formato  
inulin-for-cancer-therapy-present-and-perspectives-(1).pdf

Solo gestori archvio

Descrizione: full paper
Dimensione 473.08 kB
Formato Adobe PDF
473.08 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10447/228524
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact