The bile acid tauroursodeoxycholic acid modulates phosphorylation and translocation of bad via phosphatidylinositol 3-kinase in glutamate-induced apoptosis of rat cortical neurons

Utilize este identificador para referenciar este registo: http://hdl.handle.net/10451/21073

Título:	The bile acid tauroursodeoxycholic acid modulates phosphorylation and translocation of bad via phosphatidylinositol 3-kinase in glutamate-induced apoptosis of rat cortical neurons
Autor:	Castro, RE Sola, S Ramalho, RM Steer, CJ Rodrigues, CMP
Palavras-chave:	Pharmacology & Pharmacy
Data:	2004
Editora:	AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS
Citação:	JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. - Vol. 311, n. 2 (NOV 2004), p. 845-852
Resumo:	Neurotoxicity associated with increased glutamate release results in cell death through both necrotic and apoptotic processes. In addition, tauroursodeoxycholic acid ( TUDCA), an endogenous bile acid, is a strong modulator of apoptosis in several cell typ
URI:	http://hdl.handle.net/10451/21073
DOI:	http://dx.doi.org/10.1124/jpet.104.070532
ISSN:	0022-3565
Aparece nas colecções:	FF - Produção Científica 2000-2009

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