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The Non-specific Immunostimulation and Adjuvant Effects of Vibrio anguillarum Bacterin, M-glucan, Chitin and Freund's Complete Adjuvant against Pasteurella piscicida Infection in Yellowtail
http://hdl.handle.net/10458/1097
http://hdl.handle.net/10458/1097e13d37fc-9399-4eff-8fc5-7fa82a1462ec
名前 / ファイル | ライセンス | アクション |
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FP 33(4) 287-292 1998.pdf (2.4 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2008-01-16 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | The Non-specific Immunostimulation and Adjuvant Effects of Vibrio anguillarum Bacterin, M-glucan, Chitin and Freund's Complete Adjuvant against Pasteurella piscicida Infection in Yellowtail | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
キーワード | vaccine, immunostimulant, yellowtail, Pasteurella piscicida bacterin, M-glucan, chitin, Freund's, complete adjuvant | |||||
資源タイプ | ||||||
資源タイプ | journal article | |||||
著者 |
Kawakami, Hidemasa
× Kawakami, Hidemasa× Shinohara, Nobuyuki× 酒井, 正博 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The non-specific immunostimulation and adjuvant effects of Vibrio anguillarum bacterin (VAB), M-glucan, chitin and Freund's complete adjuvant (FCA) against pasteurellosis were examined in yellowtail, Seriola quinqueradiata. Control fish were injected intraperitoneally with 0.1 ml of sterile phosphate buffered saline (PBS). Experimental fish were injected similarly with either vaccine (lipopolysaccharide-mixed chloroformkilled Pasteurella piscicida, LPS-CKC), an immunostimulant or mixture of the vaccine and an immunostimulant. All fish were subsequently challenged by the same but live P. piscicida strain using an immersion method at 15, 25, 35 and 45 days post-inoculation. Immunostimulants alone were found to slightly increase the protection against Pasteurella infection, but the effects were not statistically significant. The most effective adjuvant was FCA, however the enhanced protection was not statistically different from that of fish inoculated with LPS-CKC alone. However, the relative percent survival (RPS) of fish vaccinated with M-glucan, chitin or Vibrio bacterin as adjuvant was lower than that of fish vaccinated with only LPS-CKC bacterin alone. Thus, M-glucan, chitin and Vibrio bacterin had no positive adjuvant effects on the P. piscicida vaccine. |
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言語 | en | |||||
書誌情報 |
ja : 魚病研究 en : Fish pathology 巻 33, 号 4, p. 287-292, 発行日 1998-10 |
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出版者 | ||||||
言語 | ja | |||||
出版者 | 日本魚病学会 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0388788X | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00063165 | |||||
著者版フラグ | ||||||
出版タイプ | VoR |