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Integrated microfluidic drug delivery devices : a component view
journal contribution
posted on 2013-07-01, 00:00 authored by Mst Fateha Samad, Abbas KouzaniAbbas KouzaniResearch on drug delivery devices is progressing rapidly with the main objective being the delivery of precise quantity of drugs into the target area of the body. A drug delivery device (DDD) needs to accurately control the flow rate of drug delivery and protects the body from undesired additional doses. An integrated microfluidic drug delivery device (IMDDD) is a miniature device that can regulate and monitor the delivery of the right amount of drug using micro-scale components. IMDDDs offer several advantages including ease of use, electro-chemical controllability, low power consumption, simplicity, fast fabrication, and good bio-compatibility. Various IMDDDs have been developed for treatment of cancer, cardiovascular disorder, eye and brain diseases, stress, and diabetes. This paper presents a generic architecture for IMDDDs, discusses the existing drug delivery methods, summarizes the specifications of the components, and identifies a number of performance evaluation parameters. The operation of IMDDDs is presented through fourteen potential internal components. In addition, recommendations on how enhance the design and fabrication process of IMDDDs are given.
History
Journal
Microsystem technologiesVolume
19Issue
7Pagination
957 - 970Publisher
SpringerLocation
Berlin, GermanyPublisher DOI
ISSN
0946-7076eISSN
1432-1858Language
engPublication classification
C1 Refereed article in a scholarly journalCopyright notice
2013, SpringerUsage metrics
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