Peroxisome biogenesis is governed by molecular machineries, which are either unique to
peroxisomes or are partially shared with mitochondria. As peroxisomes have important
protective functions in the cell, modulation of their number is important for human health and
disease. Significant progress has been made towards our understanding ...
Peroxisome biogenesis is governed by molecular machineries, which are either unique to
peroxisomes or are partially shared with mitochondria. As peroxisomes have important
protective functions in the cell, modulation of their number is important for human health and
disease. Significant progress has been made towards our understanding of the mechanisms of
peroxisome formation, revealing a remarkable plasticity of the peroxisome biogenesis
pathway. Here we discuss most recent findings with particular focus on peroxisome
formation in mammalian cells.