Interpersonal Neurobiology (IPNB) combines multiple fields of thought into one integrated framework. It has been utilized to expand conversation of the "mind" and promote well-being across disciplines. Current literature outlines the IPNB framework, including suggestions for its application to psychotherapeutic practice; however, limited research has examined clinicians' experiences of using the IPNB framework. This study aims to add to the discussion on IPNB by examining the lived experiences of psychotherapists employing IPNB as a framework for their clinical practice. This study uses thematic analysis procedures to analyze data from a focus group consisting of psychotherapeutic practitioners. The investigation explores how the participants perceive the impact of their implementation of IPNB; as well as how they believe that using the IPNB framework has changed case conceptualization and intervention. Findings and implications are also discussed.