The molecular size, charge, and solubility, distributions of natural DOC in raw and treated surface waters were investigated to determine the types of organic compounds removed by coagulation and settling. The distribution of organic precursors that react with chlorine to form organic halide compounds was also determined, along with the reaction rates. DOC removal by coagulation was size dependent. Compounds over 5,000 d were readily removed while compounds under 1,000 d were largely unaffected. Acidic and basic molecules were precipitated much more effectively than neutral ones. Both hydrophilic and hydrophobic molecules were selectively removed compared to compounds of intermediate solubility. Two groups of organic halide precursors were identified. Fulvic acids had high specific organic halide yields, and fast reaction rates with chlorine, but could be effectively removed by coagulation. Nonpolar neutral compounds were lower in molecular weight, slower to react with chlorine, and produced less organic halide, but could not be precipitated by coagulation.