The article examines the application of a geographical information system (GIS) project to the sustainable development of a natural resource within the context of a fisheries production system in the Central Delta of the River Niger in Mali. The project, which takes into account the specific characteristics of the natural and social environment, results from the findings of a research programme carried out between 1986-94 to investigate the organization and dynamics of a production sector which is based on the exploitation of a natural renewable resource. The Central Delta of the Niger contributes around 90% annually of total fish production in Mali. Over recent years, however, increasing interest from developers, restrictions on fishing and conflict between producers have caused a crisis of production. Through the development of a system of spatial representation of the interactions between the social and natural systems of the area, the objectives of the GIS are to solve the conflicts associated with resource use, develop an effective system of resource management and ensure the long term sustainability of the resource. (CAB Abstract)