Synthesis and Characterization of Two Nanoparticle Platforms : Gold and Alginate
Loading...
Authors
DuRoss, Erin L.
Issue Date
2016
Type
Thesis
Language
en_US
Keywords
Alternative Title
Abstract
Nanoscience and Cancer Biology are currently being combined in pharmaceutical research to help lead the fight against diseases such as cancer. The engineering of nanoparticles for targeted drug delivery has been a major component of this, largely due to the Enhanced Permeation and Retention effect. This paper proposes a new method for preparing alginate nanoparticles for drug delivery, using a water-in-oil emulsion method and utilizing alginate’s capability of cross-linking with calcium. While particles of the desired size were successfully synthesized, repeatability was unable to be obtained within the scope of this research. In addition, this thesis studies an established platform of gold nanoclusters, with the intent of encapsulating the gold nanoclusters within the alginate particles in future experiments.
Description
vii, 28 p.
Citation
Publisher
Kalamazoo College
License
U.S. copyright laws protect this material. Commercial use or distribution of this material is not permitted without prior written permission of the copyright holder. All rights reserved.