Monoclonal antibodies to intra-acrosomal proteins inhibit gamete binding

0191232 - UMG-J 20010303 RIV US eng J - Článek v odborném periodiku
Pěknicová, Jana - Čapková, Jana - Geussová, Gizela - Ivanova, M. - Mollova, M.
Monoclonal antibodies to intra-acrosomal proteins inhibit gamete binding.
Theriogenelogy. Roč. 56, č. 2 (2001), s. 211-223. ISSN 0093-691X. E-ISSN 1879-3231
Grant CEP: GA ČR GV524/96/K162; GA ČR GA303/00/1651; GA MZd NJ5851
Klíčová slova: secondary sperm-zona pellucida binding * intraacrosomal proteins * acrosin
Kód oboru RIV: EB - Genetika a molekulární biologie
Impakt faktor: 1.965, rok: 2001

The sperm-zona pellucida-binding assay in vitro was used as a functional test for zona pellucida-binding ability of boar spermatozoa after co-incubation with monoclonal antibodies against intra-acrosomal proteins to reduce the secondary sperm-zona pellucida-binding with statistically significant difference. This suggests the role of these proteins in the early phases of fertilization.
Trvalý link: http://hdl.handle.net/11104/0086988