Počet záznamů: 1
Structure and function of nuclear myosin
- 1.0321754 - ÚMG 2009 GB eng A - Abstrakt
Kahle, Michal - Kalendová, Alžběta
Structure and function of nuclear myosin.
[Struktura a funkce jaderného myosinu.]
Alternative Muscle Club. Leeds: University of Leeds, 2008. s. 36-36.
[Alternative Muscle Club /26th/. 23.07.2008-25.07.2008, Leeds]
Grant CEP: GA ČR(CZ) GA204/07/1592; GA MŠMT LC545
Grant ostatní: MŠMT(CZ) LC06063
Program: LC
Výzkumný záměr: CEZ:AV0Z50520514
Klíčová slova: nuclear mysion
Kód oboru RIV: EB - Genetika a molekulární biologie
The research is focused on the function of a nuclear isoform of myosin molecular motor - nuclear myosin I (NM1). This nuclear motor was shown to be involved in transcription, chromatin remodelling and repositioning of transcriptionaly activated regions in the nucleoplasm. NM1 differs from its cytoplasmic variant myosin IC by a unique N-terminal extension of unknown function. We are interested in the structure of the motor domain of NM1 and the relation to the N-terminal domain as it could elucidate the specific properties of the molecule that allow it to perform its nuclear roles.
Trvalý link: http://hdl.handle.net/11104/0170199
Počet záznamů: 1