New peptides with antimicrobial activity isolated from the venom of the bumblebee Bombus pascuorum (Hymenoptera: Apidae)

0338112 - ÚOCHB 2011 CZ eng C - Konferenční příspěvek (zahraniční konf.)
Ježek, Rudolf - Janechová, D. - Cvačka, Josef - Slaninová, Jiřina - Voburka, Zdeněk - Hovorka, Oldřich - Fučík, Vladimír - Borovičková, Lenka - Maloň, Petr - Čeřovský, Václav
New peptides with antimicrobial activity isolated from the venom of the bumblebee Bombus pascuorum (Hymenoptera: Apidae).
Biologically Active Peptides. 11th Conference. Praha: Institut of organic Chemistry and Biochemistry ASCR, 2009 - (Slaninová, J.), s. 51-54. Collection Symposium Series, 11. ISBN 978-80-86241-31-9.
[Biologically Active Peptides. Conference /11./. Praha (CZ), 22.04.2009-24.04.2009]
Grant CEP: GA ČR(CZ) GA203/08/0536
Výzkumný záměr: CEZ:AV0Z40550506
Klíčová slova: antimicrobial peptides * alpha-helical structure * amphipathic molecule * Bombus pascuorum
Kód oboru RIV: CC - Organická chemie

Six new heptadecapeptides were isolated and synthesized by standard Fmoc solid phase peptide synthesistogether with several structural analogues. Antimicrobial activities were correlated with the peptides hydrophobicity, hydrophobic moment, alpha-helicity and HPLC retention time.
Trvalý link: http://hdl.handle.net/11104/0181970