Introductory Biophysics: Perspectives on the Living State

0351867 - ÚEM 2011 US eng M - Část monografie knihy
Blažíková, Michaela - Malínský, Jan - Staněk, D. - Heřman, D.
Modeling of snRNP Motion in the Nucleoplasm.
Introductory Biophysics: Perspectives on the Living State. Boston: Jones & Bartlett Publishers, 2010, s. 48-51. ISBN 978-0-7637-7998-6
Výzkumný záměr: CEZ:AV0Z50390512
Klíčová slova: snRNP
Kód oboru RIV: EB - Genetika a molekulární biologie

The article deals with the dynamics of the assembly and movement of snRNPs inside the cell nucleus. The in vivo snRNP dynamics was tested in the frame of a simple diffusion model, which was used to fit experimental values. The results of fits to analytical solutions of the diffusion equation indicate that the simple diffusion model is not consistent with the experimental data, a correction of the model was therefore proposed.
Trvalý link: http://hdl.handle.net/11104/0191515