Počet záznamů: 1
Inhibition of human thymidine phosphorylase by phosphonate analogues of pyrimidine nucleoside 2’(3’)-phosphates
- 1.0353488 - ÚOCHB 2011 FR eng C - Konferenční příspěvek (zahraniční konf.)
Panova, Natalya - Markusová Kóšiová, Ivana - Šimák, Ondřej - Petrová, Magdalena - Liboska, Radek - Buděšínský, Miloš - Rejman, Dominik - Rosenberg, Ivan
Inhibition of human thymidine phosphorylase by phosphonate analogues of pyrimidine nucleoside 2’(3’)-phosphates.
International Roundtable on Nucleosides, Nucleotides and Nucleic Acids. IRT 2010. Lyon: Université de Lyon, 2010, s. 336-337.
[International Roundtable on Nucleosides, Nucleotides and Nucleic Acids. IRT 2010. Lyon (FR), 29.08.2010-03.09.2010]
Grant CEP: GA MŠMT(CZ) LC06077; GA AV ČR KAN200520801; GA MŠMT(CZ) LC06061
Výzkumný záměr: CEZ:AV0Z40550506
Klíčová slova: human thymidine phosphorylase * phosphorylase inhibition * phosphonate nucleosides
Kód oboru RIV: CC - Organická chemie
http://irt2010.univ-lyon1.fr
A series of structurally diverse nucleoside phosphonic acids were tested for inhibition of human thymidine phosphorylase from two sources. Some inhibitors acting at submicromolar level were selected as lead structures for further evaluation.
Trvalý link: http://hdl.handle.net/11104/0192731
Počet záznamů: 1