Počet záznamů: 1
Synthesis of novel azanorbornylpurine derivatives
- 1.0376064 - ÚOCHB 2013 RIV GB eng J - Článek v odborném periodiku
Hřebabecký, Hubert - Dejmek, Milan - Dračínský, Martin - Šála, Michal - Leyssen, P. - Neyts, J. - Kaniaková, Martina - Krůšek, Jan - Nencka, Radim
Synthesis of novel azanorbornylpurine derivatives.
Tetrahedron. Roč. 68, č. 4 (2012), s. 1286-1298. ISSN 0040-4020. E-ISSN 1464-5416
Grant CEP: GA MŠMT 1M0508; GA ČR(CZ) GA202/09/0806; GA MŠMT(CZ) LC554
Výzkumný záměr: CEZ:AV0Z40550506; CEZ:AV0Z50110509
Klíčová slova: azanorbornane * purines * coxsackievirus
Kód oboru RIV: CC - Organická chemie
Impakt faktor: 2.803, rok: 2012
Novel racemic derivatives of 6-chloropurine, adenine, and 6-(cyclopropylamino)purine substituted with 2-azanorbornane, 7-azanorbornane, and 7-azabenzonorbornane were synthesized. All target compounds were tested for antiviral activity (CVB3, HCV) and 6-chloropurine derivatives were evaluated for potential activity as agonists of the neuronal and muscle nicotinic acetylcholine receptor.
Trvalý link: http://hdl.handle.net/11104/0208565
Počet záznamů: 1