Počet záznamů: 1
Compartment- and malignance-dependent up-regulation of gamma-glutamyltranspeptidase and dipetidylpeptidase-IV activity in human brain gliomas
- 1.0380301 - FGÚ 2013 RIV ES eng J - Článek v odborném periodiku
Mareš, Vladislav - Stremeňová, J. - Lisá, Věra - Kozáková, Hana - Marek, J. - Syrůček, M. - Šoula, O. - Šedo, A.
Compartment- and malignance-dependent up-regulation of gamma-glutamyltranspeptidase and dipetidylpeptidase-IV activity in human brain gliomas.
Histology and Histopathology. Roč. 27, č. 7 (2012), s. 931-940. ISSN 0213-3911. E-ISSN 1699-5848
Výzkumný záměr: CEZ:AV0Z50110509; CEZ:AV0Z50200510
Klíčová slova: gamma-glutamyltranspeptidase * dipeptidylpeptidase IV-like activity * CD26 * FAP-1 alpha * human gliomas
Kód oboru RIV: FD - Onkologie a hematologie
Impakt faktor: 2.281, rok: 2012
The grade of malignance-dependent increase of enzyme activity/expression of gamma-glutamyltranspeptiase (GGT) and dipeptidylpeptidase IV (DPP-IV)-like activity, including CD26 and FAP-1 alpha was found in human gliomas. They seem to participate in maintenance of redox potential, proliferation and tumor microenviroment control expressed primarily at the microvasculature/parenchyma interface. These activities/molecules correlated with post-operation survival time of a minor subgroup of patients with glioblastoma
Trvalý link: http://hdl.handle.net/11104/0211042
Počet záznamů: 1