Počet záznamů: 1
Redox Homeostasis in Pancreatic beta Cells
- 1.0389998 - FGÚ 2013 RIV US eng J - Článek v odborném periodiku
Ježek, Petr - Dlasková, Andrea - Plecitá-Hlavatá, Lydie
Redox Homeostasis in Pancreatic beta Cells.
Oxidative Medicine and Cellular Longevity. Roč. 2012, č. 2012 (2012), s. 932838. ISSN 1942-0900. E-ISSN 1942-0994
Grant CEP: GA ČR(CZ) GAP302/10/0346; GA ČR(CZ) GPP304/10/P204
Institucionální podpora: RVO:67985823
Klíčová slova: beta cells * reactive oxygen species homeostasis * mitochondria
Kód oboru RIV: FB - Endokrinologie, diabetologie, metabolizmus, výživa
Impakt faktor: 3.393, rok: 2012
In this article authors reviewed mechanism that determine reactive oxygen species (redox) homeostasis, redox information signaling and metabolic/regulatory function of autocrine insulin signaling in pancreatic beta cells, and consequences of oxidative stress and dysregulation of redox/information signaling for their dysfunction. They emphasized the role of mitochondrion in beta cell molecular physiology and pathology, including the antioxidant role of mitochondrial uncoupling protein 2
Trvalý link: http://hdl.handle.net/11104/0218888
Počet záznamů: 1