Počet záznamů: 1
Cellulose-based materials as scaffolds for tissue engineering
- 1.0396434 - FGÚ 2014 RIV NL eng J - Článek v odborném periodiku
Novotná, Katarína - Havelka, P. - Sopuch, T. - Kolářová, K. - Vosmanská, V. - Lisá, Věra - Švorčík, V. - Bačáková, Lucie
Cellulose-based materials as scaffolds for tissue engineering.
Cellulose. Roč. 20, č. 5 (2013), s. 2263-2278. ISSN 0969-0239. E-ISSN 1572-882X
Grant CEP: GA ČR(CZ) GAP108/12/1168; GA MPO(CZ) 2A-1TP1/073
Výzkumný záměr: CEZ:AV0Z50110509
Institucionální podpora: RVO:67985823
Klíčová slova: polysacharide materials * oxidized cellulose * vascular smooth muscle cells * chitosan
Kód oboru RIV: FR - Farmakologie a lékárnická chemie
Impakt faktor: 3.033, rok: 2013
The results that we have obtained indicate that oxidized cellulose with 2.1 wt% of –COOH groups could be an appropriate material for tissue engineering, due to its relatively high stability during manipulation and exposure to the cell culture environment, and its biocompatibility, which can be further improved by modification with biomolecules, particularly chitosan. As it induces the most appropriate spreading and phenotypic maturation of cells, but not considerable cell proliferation, it could be used in the construction of bioartificial tissues or organs, where high proliferation activity of cells is not desired. A possible application of this material is for constructing bioartificial vascular protheses, where excessive growth activity of cells on the material may cause stenosis and failure of these replacement
Trvalý link: http://hdl.handle.net/11104/0224255
Počet záznamů: 1