Počet záznamů: 1
Acoustical enrichment during early postnatal development changes response properties of inferior colliculus neurons in rats
- 1.0435620 - ÚEM 2015 RIV GB eng J - Článek v odborném periodiku
Bureš, Zbyněk - Bartošová, Jolana - Lindovský, Jiří - Chumak, Tetyana - Popelář, Jiří - Syka, Josef
Acoustical enrichment during early postnatal development changes response properties of inferior colliculus neurons in rats.
European Journal of Neuroscience. Roč. 40, č. 11 (2014), s. 3674-3683. ISSN 0953-816X. E-ISSN 1460-9568
Grant CEP: GA ČR(CZ) GAP303/12/1347; GA ČR(CZ) GBP304/12/G069; GA MŠMT EE2.3.30.0018
Institucionální podpora: RVO:68378041
Klíčová slova: attention-dependent plasticity * auditory system * critical period
Kód oboru RIV: FH - Neurologie, neurochirurgie, neurovědy
Impakt faktor: 3.181, rok: 2014
This study explores the effects of an acoustically enriched environment applied during the third and fourth week of life on the responsiveness of inferior colliculus neurons in rats. The exposure permanently influenced neuronal representation of the sound frequency and intensity, resulting in lower excitatory thresholds at neuronal characteristic frequency, an increased frequency selectivity, larger response magnitudes, steeper rate-intensity functions and an increased spontaneous activity. These findings indicate that a rich and stimulating acoustic environment during early development, particularly when reinforced by positive feedback, may permanently affect signal processing in the subcortical auditory nuclei.
Trvalý link: http://hdl.handle.net/11104/0240967
Počet záznamů: 1