Smart polymers in drug delivery systems on crossroads: which way deserves following?

0442919 - ÚMCH 2016 RIV GB eng J - Článek v odborném periodiku
Hrubý, Martin - Filippov, Sergey K. - Štěpánek, Petr
Smart polymers in drug delivery systems on crossroads: which way deserves following?
European Polymer Journal. Roč. 65, April (2015), s. 82-97. ISSN 0014-3057. E-ISSN 1873-1945
Grant CEP: GA ČR GAP304/12/0950; GA MŠMT(CZ) LH14292; GA MŠMT(CZ) 7F14009; GA ČR(CZ) GA13-08336S
Institucionální podpora: RVO:61389013
Klíčová slova: stimuli responsive polymers * drug delivery * thermosensitive polymers
Kód oboru RIV: CC - Organická chemie
Impakt faktor: 3.485, rok: 2015

A feature article is presented on recent developments in the investigation of stimuli responsive polymers and their biomedical applications. Polymer systems are grouped with respect to sensitivity to changes in temperature, pH, light, redox potential and other special changes in environment. Underlying principles and possible applications of various systems are discussed. Critical evaluation of all benefits but also drawbacks of a particular stimuli responsivity is therefore necessary when planning the construction of multi-stimuli responsive systems. Special focus is devoted to biological consequences of physico-chemical properties of the polymer materials.
Trvalý link: http://hdl.handle.net/11104/0246256