Diverse development and higher sensitivity of the circadian clocks to changes in maternal-feeding regime in a rat model of cardio-metabolic disease

0446426 - FGÚ 2016 RIV GB eng J - Článek v odborném periodiku
Olejníková, Lucie - Polidarová, Lenka - Paušlyová, Lucia - Sládek, Martin - Sumová, Alena
Diverse development and higher sensitivity of the circadian clocks to changes in maternal-feeding regime in a rat model of cardio-metabolic disease.
Chronobiology International. Roč. 32, č. 4 (2015), s. 531-547. ISSN 0742-0528. E-ISSN 1525-6073
Grant CEP: GA ČR(CZ) GAP303/12/1108
Grant ostatní: Program interní podpory projektů mezinárodní spolupráce AV ČR(CZ) M200111202
Institucionální podpora: RVO:67985823
Klíčová slova: circadian clock * clock gene * colon * liver * SHR * supraciasmatic nucleus
Kód oboru RIV: ED - Fyziologie
Impakt faktor: 3.540, rok: 2015

This study was aimed to elucidate how the SHR circadian system develops during ontogenesis. Our findings revealed diverse development and higher sensitivity of the developing circadian clocks of SHR to maternal cues. They suggested that these aberrancies might contribute to the metabolic disease, which SHR spontaneously develop in adulthood
Trvalý link: http://hdl.handle.net/11104/0248424