Počet záznamů: 1
Role of trade-off between sexual and vertical routes for evolution of pathogen transmission
- 1.0446617 - BC 2016 RIV DE eng J - Článek v odborném periodiku
Bernhauerová, V. - Berec, Luděk
Role of trade-off between sexual and vertical routes for evolution of pathogen transmission.
Theoretical Ecology. Roč. 8, č. 1 (2015), s. 23-36. ISSN 1874-1738. E-ISSN 1874-1746
Grant ostatní: Masaryk University(CZ) MUNI/A/0849/2012
Institucionální podpora: RVO:60077344
Klíčová slova: adaptive dynamics * frequency-dependent transmission * infectious disease
Kód oboru RIV: EH - Ekologie - společenstva
Impakt faktor: 2.085, rok: 2015
http://link.springer.com/article/10.1007%2Fs12080-014-0234-8
Using an empirically suggested trade-off between the horizontal and vertical transmission modes, we develop and analyze a model to study evolutionary dynamics of sterilizing, sexually transmitted infections which can also be transmitted vertically. Assuming several flexible forms of the trade-off, our evolutionary analysis reveals a rich spectrum of evolutionary outcomes. In particular, evolution of pure sexual, pure vertical and mixed transmission is possible, in addition to a frequent occurrence of evolutionary suicide. These outcomes can also arise via evolutionary branching and be combined in several evolutionary bistability regimes. We also show that the shape of the trade-off between the two transmission modes significantly affects pathogen evolution; while vertical transmission dominates for concave and sigmoid trade-offs, sexual transmission is most commonly observed under convex trade-offs.
Trvalý link: http://hdl.handle.net/11104/0248587
Počet záznamů: 1