Two SAPP2 gene homologs are present in Candida parapsilosis genome

0446961 - ÚOCHB 2016 RIV CZ eng J - Článek v odborném periodiku
Dostál, Jiří - Merkerová, M. - Vinterová, Zuzana - Pichová, Iva - Hrušková-Heidingsfeldová, Olga
Two SAPP2 gene homologs are present in Candida parapsilosis genome.
Folia Microbiologica. Roč. 60, č. 5 (2015), s. 373-374. ISSN 0015-5632. E-ISSN 1874-9356
Grant CEP: GA ČR(CZ) GA14-23022S; GA MŠMT LO1302
Institucionální podpora: RVO:61388963
Klíčová slova: aspartic proteinases * Candida parapsilosis * opportunistic pathogen
Kód oboru RIV: EE - Mikrobiologie, virologie
Impakt faktor: 1.335, rok: 2015

Candida parapsilosis produces secreted aspartic proteinases (Saps), which contribute to the virulence of this opportunistic pathogen. Gene family containing as many as 14 sequences potentially encoding secreted aspartic proteinases was identified in C. parapsilosis genome. Of them, SAPP1 and SAPP2 genes have been extensively characterized, but only now do we report that two SAPP2 homologs sharing 91.5% identity occur in C. parapsilosis genome. Existence of SAPP2 homologs points to unexpected complexity of the SAPP gene family.
Trvalý link: http://hdl.handle.net/11104/0248930