Počet záznamů: 1
Nano-structured and functionalized surfaces for cytocompatibility improvement and bactericidal action
- 1.0449225 - FGÚ 2016 RIV US eng J - Článek v odborném periodiku
Slepička, P. - Kasálková-Slepičková, N. - Siegel, J. - Kolská, Z. - Bačáková, Lucie - Švorčík, V.
Nano-structured and functionalized surfaces for cytocompatibility improvement and bactericidal action.
Biotechnology Advances. Roč. 33, 6 Part 2 (2015), s. 1120-1129. ISSN 0734-9750. E-ISSN 1873-1899
Grant CEP: GA ČR(CZ) GBP108/12/G108
Institucionální podpora: RVO:67985823
Klíčová slova: polymers * surface modification * cell-material interaction * tissue engineering
Kód oboru RIV: JJ - Ostatní materiály
Impakt faktor: 9.848, rok: 2015
Not only surface chemistry has an effect on material biological response, surface structures of different morphology can be constructed to guide a desirable biological outcome. Nano-patterned material surfaces have been tested with the aim of how surface geometry and physical properties on a micro- and nano-scale can effect cellular response and influence cell adhesion and proliferation. Biological functionality of solid state substrates was significantly improved by the irradiation of material with plasma discharge or laser treatment. Commonly used “artificial” polymers were treated with the aim of biocompatibility improvement. Surface physico-chemical properties of treated surfaces were determined. The enhancement of adhesion and proliferation of cells on modified substrates was investigated in vitro. Bacterial action of noble metal nano-particles (e.g. Au, Ag) on polymers was characterized. The influence of metal nano-particle grafting by using metal nano-particle suspension prepared by “green” methods was determined. Micro. And nano-patterned surfaces can be constructed as tissue scaffolds with specific functions regarding cell adhesion and proliferation or potential biosensor applications
Trvalý link: http://hdl.handle.net/11104/0250816
Počet záznamů: 1