"Non-Taxifolin" Derived Flavonolignans: Phytochemistry and Biology

0452940 - MBÚ 2016 RIV GB eng J - Článek v odborném periodiku
Chambers, Christopher S. - Valentová, Kateřina - Křen, Vladimír
"Non-Taxifolin" Derived Flavonolignans: Phytochemistry and Biology.
Current Pharmaceutical Design. Roč. 21, č. 38 (2015), s. 5489-5500. ISSN 1381-6128. E-ISSN 1873-4286
Grant CEP: GA MŠMT LH13097; GA MŠMT(CZ) LD14096; GA ČR(CZ) GA15-03037S; GA MŠMT(CZ) LD15084
Institucionální podpora: RVO:61388971
Klíčová slova: Taxifolin * quercetin * luteolin
Kód oboru RIV: CE - Biochemie
Impakt faktor: 3.052, rok: 2015

Flavonolignans are plant natural products, composed of a flavonoid moiety and a lignan (phenylpropanoid) part. Current literature focuses on flavonolignans formed from taxifolin and coniferyl alcohol as e.g. silybin and its congeners from fruit extract from the purple variety of the milk thistle (Silybum marianum) denoted as "silymarin". This review describes chemistry and biological activity of so far neglected "non-taxifolin" based flavonolignans, derived from apigenin, luteolin, tricin, chrysoeriol, naringenin and eriodictyol, as the flavonoid part. Up-to-date knowledge on hydnocarpin, hydnocarpin-D, pseudotsuganol, hydnowightin, neohydnocarpin, palstatin, salcolins A and B, anastatins A and B, sinaiticin, silyamandin and silandrin is summarized in the present paper.
Trvalý link: http://hdl.handle.net/11104/0253831