Gene copy number variation across the hybrid zone of the house mouse (Mus musculus)

0454470 - ÚBO 2017 CZ eng A - Abstrakt
Yanchukov, Alexey - Baird, Stuart J. E. - Hiadlovská, Zuzana - Pezer, Z. - Macholán, M. - Piálek, Jaroslav
Gene copy number variation across the hybrid zone of the house mouse (Mus musculus).
Zoologické dny Brno 2015: sborník abstraktů z konference 12.-13. února 2015. Brno: Ústav biologie obratlovců AV ČR, 2015 - (Bryja, J.; Řehák, Z.; Zukal, J.). s. 266-267. ISBN 978-80-87189-18-4.
[Zoologické dny. 12.02.2015-13.02.2015, Brno]
Institucionální podpora: RVO:68081766
Klíčová slova: house mouse * hybrid zone
Kód oboru RIV: EG - Zoologie

Polymorphism in gene copy number can reflect recent phylogeographic history of populations as well as contribute to adaptation. In the hybrid zone of the two mouse subspecies, we aim to explore the CNV of a subset of protein-coding genes located within the regions of extensive introgression across the species barrier compared to the regions of limited introgression. The initial part of the study involved the choice of the candidate loci based on the existing data of mouse genome structural variation found in the public databases, and we began genotyping the CNV of a few genes known to play a role in the developmental and physiological processes that are likely to affect the maintenance of the species barrier.
Trvalý link: http://hdl.handle.net/11104/0255166