Hantavirus strains in East Africa related to Western African hantaviruses

0469992 - ÚBO 2018 RIV US eng J - Článek v odborném periodiku
Těšíková, Jana - Bryjová, Anna - Bryja, Josef - Lavrenchenko, L. A. - Goüy de Bellocq, Joëlle
Hantavirus strains in East Africa related to Western African hantaviruses.
Vector-Borne and Zoonotic Diseases. Roč. 17, č. 4 (2017), s. 278-280. ISSN 1530-3667. E-ISSN 1557-7759
Grant CEP: GA ČR GCP502/11/J070
Institucionální podpora: RVO:68081766
Klíčová slova: bats * East Africa * hantavirus * phylogeny * rodents
Obor OECD: Infectious Diseases
Impakt faktor: 2.171, rok: 2017

Hantaviruses are RNA viruses primarily carried by rodents, soricomorphs, and bats. The data about the distribution and genetic diversity of these viruses are often limited, especially inmost regions of sub-Saharan Africa. Moreover, themajority of representatives were identified inwesternAfrican localities, while only three hantaviruses have been reported in East Africa to date. In this study, a total of 1866 small mammals captured between 2009 and 2014 in various countries of Eastern Africa (Ethiopia, Zambia, Mozambique, Kenya, and Tanzania) were molecularly screened for the presence of hantaviruses. Hantavirus RNA was detected in dried blood samples of the Cape pipistrelle bat (Neoromicia capensis) captured in Ethiopia and the African wood mouse (Hylomyscus endorobae) from Kenya. Phylogenetic analysis of partial genomic segments revealed that the Ethiopian sample represents a sister lineage of the Mouyassue´ virus (reported previously from the congeneric bat in Cote d’Ivoire), and the Kenyan sample is a sister lineage of the Sangassou virus (described from the same mouse genus in Guinea).
Trvalý link: http://hdl.handle.net/11104/0267738