Increased transgenerational epigenetic variation, but not predictable epigenetic variants, after environmental exposure in two apomictic dandelion lineages

0495223 - BÚ 2019 RIV US eng J - Článek v odborném periodiku
Preite, V. - Oplaat, C. - Biere, A. - Kirschner, Jan - van der Putten, W.H. - Verhoeven, K. J. F.
Increased transgenerational epigenetic variation, but not predictable epigenetic variants, after environmental exposure in two apomictic dandelion lineages.
Ecology and Evolution. Roč. 8, č. 5 (2018), s. 3047-3059. ISSN 2045-7758. E-ISSN 2045-7758
Grant CEP: GA ČR GA13-13368S
GRANT EU: European Commission(XE) 613697 - DRIVE4EU
Institucionální podpora: RVO:67985939
Klíčová slova: epigenetics * DNA methylation * Taraxacum sect. Taraxacum
Obor OECD: Plant sciences, botany
Impakt faktor: 2.415, rok: 2018

DNA methylation, one of the mechanisms underlying epigenetic modifications, can be environmentally induced nad the change may become heritable. Taraxacum apomicts, with their maternal inheritance, are suitable models for testing the frequency and durability of the changes. Irrespective of the initial stress treatment, a clear buildup of heritable DNA methylation variation was observed across three generations, indicating a considerable background rate of heritable epimutations. Less evidence was detected for environmental effects. Drought stress showed some evidence for accession-specific methylation changes, but only in the exposed generation and not in their offspring. Our study shows that (1) stress-induced transgenerational DNA methylation modification in dandelions is genotype and context-specific, and (2) inherited environmental DNA methylation effects are mostly undirected and not targeted to specific loci.
Trvalý link: http://hdl.handle.net/11104/0290089