Genomic analysis finds no evidence of canonical eukaryotic DNA processing complexes in a free-living protist

0554929 - BC 2022 RIV GB eng J - Článek v odborném periodiku
Salas-Leiva, D. - Tromer, E. - Curtis, B.A. - Jerlstrom-Hultqvist, J. - Kolísko, Martin - Yi, Z. - Salas-Leiva, J.S. - Gallot-Lavallee, L. - Williams, S. - Kops, G. - Archibald, J.M. - Simpson, A. - Roger, A.
Genomic analysis finds no evidence of canonical eukaryotic DNA processing complexes in a free-living protist.
Nature Communications. Roč. 12, č. 1 (2021), č. článku 6003. E-ISSN 2041-1723
Institucionální podpora: RVO:60077344
Klíčová slova: spindle assembly checkpoint * origin recognition complex * homologous recombination * evolutionary dynamics * kinetochore proteins * ribonuclease h * replication * giardia * repair * conservation
Obor OECD: Zoology
Impakt faktor: 17.694, rok: 2021
Způsob publikování: Open access
https://www.nature.com/articles/s41467-021-26077-2

The mechanisms for replicating and segregating DNA are highly conserved across eukaryotes. A comparative genomic analysis of a free-living protist finds a surprising lack of protein complexes involved in these processes, suggesting that the organism uses alternative mechanisms to process DNA.
Trvalý link: http://hdl.handle.net/11104/0329547