- Author
-
H. Devlin
P. Allen
J. Graham
R. Jacobs
K. Nicopoulou-Karayianni
C. Lindh
E. Marjanovic
J. Adams
S. Pavitt
P. van der Stelt
K. Horner - Year
- 2008
- Title
- The role of the dental surgeon in detecting osteoporosis: the OSTEODENT study
- Journal
- British Dental Journal
- Volume | Issue number
- 204 | 10
- Pages (from-to)
- E16; 560-561
- Number of pages
- 6
- Document type
- Article
- Faculty
- Faculty of Dentistry (ACTA)
- Abstract
-
Objective: To determine if thinning (<3 mm width) of the lower cortical border of the mandible on dental panoramic radiographs, as well as other clinical risk factors, may provide a useful diagnostic test for osteoporosis in young postmenopausal women.
Design: Six hundred and fifty-two subjects (age range 45-70 years) were involved in this multi-centre, cross-sectional study.
Setting: Patients were recruited from centres in Leuven (Belgium), Athens (Greece), Manchester (UK), and Malmo (Sweden).
Subjects and methods: The subject's age, body weight, whether the patient took hormone replacement therapy or had a history of low trauma fracture were used to form a clinical osteoporosis risk assessment (the OSteoporosis Index of RISk or OSIRIS index). Each patient also received a dental panoramic radiographic examination.
Results: One hundred and forty subjects had osteoporosis involving at least one of the measurement sites (lumbar spine, femoral neck or total hip). Those with osteoporosis tended to have a low OSIRIS score and a thinned cortical mandibular border. The area under the ROC curve for using both cortical width and OSIRIS to predict osteoporosis was 0.90 (95% CI = 0.87 to 0.92). There was a significant improvement in the diagnostic ability of the combined OSIRIS and cortical width test over both tests applied separately (p <0.001). The cost effectiveness of the cortical width and OSIRIS model was improved by using a high specificity threshold rather than high sensitivity. However, this analysis ignores the costs associated with missed cases of osteoporosis.
Conclusion: Dentists have a role to play in the detection and referral of patients at high risk of osteoporosis. - URL
- go to publisher's site
- Language
- Undefined/Unknown
- Note
- summary: http://dx.doi.org/10.1038/sj.bdj.2008.427
- Persistent Identifier
- https://hdl.handle.net/11245/1.301431
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