- Author
-
J.J. Molenaar
- Title
- The cell cycle in neuroblastoma : from genomic aberrations to targeted intervention
- Supervisors
-
H.N. Caron
R Versteeg - Award date
- 18 September 2009
- Number of pages
- 132
- ISBN
- 9789090245003
- Document type
- PhD thesis
- Faculty
- Faculty of Medicine (AMC-UvA)
- Persistent Identifier
- https://hdl.handle.net/11245/1.323237
- Downloads
-
Thesis
Front cover
Title pages
Contents
Chapter 1: Introduction
Chapter 2: Rearrangements and increased expression of Cyclin D1 in neuroblastoma
Chapter 3: Cyclin D1 is a direct transcriptional target of GATA3 in neuroblastoma tumor cells
Chapter 4: Cyclin D1 and CDK4 activity contribute to the undifferentiated phenotype in neuroblastoma
Chapter 5: High frequency of genetic aberrations of G1 regulating cell cycle genes in neuroblastoma is related to high expression of G2/M phase E2F target genes and worse prognosis
Chapter 6: Inactivation of CDK2 is synthetically lethal to MYCN over-expressing cancer cells
Chapter 7: Discussion and future directions
Chapter 8: Nederlandse samenvatting en dankwoord
Back cover
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