- Author
-
P. Chockalingam
- Title
- Addressing the diagnostic and therapeutic challenges in inheritable arrhythmia syndromes: with emphasis on the pediatric population
- Supervisors
-
A.A.M. Wilde
N.A. Blom - Co-supervisors
-
S.A.B. Clur
- Award date
- 5 September 2012
- Number of pages
- 141
- ISBN
- 9789461821423
- Document type
- PhD thesis
- Faculty
- Faculty of Medicine (AMC-UvA)
- Abstract
-
This thesis addresses some of the most pressing issues and challenges in the management of congenital long QT syndrome and loss-of-function sodium channelopathies, with a special focus on the pediatric population. With inheritable arrhythmia syndromes emerging as an important piece in the puzzle of sudden unexplained death, the findings of the studies described here have relevant implications in different spheres of clinical practice, namely improved awareness, accurate diagnosis and effective treatment.
- Note
- Research conducted at: Universiteit van Amsterdam
- Persistent Identifier
- https://hdl.handle.net/11245/1.385927
- Downloads
-
Thesis
Cover
Title pages
Table of contents
Chapter 1: General introduction
Chapter 2: The role of the epinephrine test in the diagnosis and management of children suspected of having congenital long QT syndrome
Chapter 3: Derivation and validation of a simple exercise-based algorithm for prediction of genetic testing in relatives of LQTS probands
Chapter 4: Diagnosis of congenital long QT syndrome: do all clinically suspected patients warrant genetic testing?
Chapter 5: Not all beta-blockers are equal in the management of long QT syndromes types 1 and 2: higher recurrence of events under metoprolol
Chapter 6: Fever induced life-threatening arrhythmias in children harboring an SCN5A mutation
Chapter 7: The diagnostic and therapeutic aspects of loss-of-function cardiac sodium channelopathies in children
Chapter 8: Idiopathic ventricular fibrillation in two infants, not always idiopathic on follow-up
Chapter 9: Summary and conclusions
Chapter 10: Samenvatting
About the author
Acknowledgements
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